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Fig. 3 | Maxillofacial Plastic and Reconstructive Surgery

Fig. 3

From: The presence and distribution of various genes in postnatal CLP-affected palatine tissue

Fig. 3

SOX3, WNT3A and WNT9B gene visualization in cleft-affected palatine tissue of patients using chromogenic in situ hybridization method and immersion oil. a A tissue sample of a 10-month-old child with a moderate (+ +) number of gene signals in the epithelium, occasional (0/ +) gene signals in the connective tissue, and no (0) gene signals in the endothelium. SOX3 CISH, × 400. b A tissue sample of a 15-month-old child with numerous (+ + +) gene signals in the epithelium, occasional (0/ +) gene signals in the connective tissue, and no (0) gene signals in the endothelium. WNT3A CISH, × 400. c A tissue sample of a 15-month-old child with numerous to abundant (+ +  + / +  +  + +) gene-signal-containing cells in the epithelium, a few ( +) gene signals in the connective tissue, and no (0) gene-signal-containing cells in the endothelium. WNT9B CISH, × 400

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