Maxillofacial Plastic and Reconstructive Surgery

Table 4 Immunohistochemistry analysis of collagen type I, OPG and RANKL

From: Combined effect of bisphosphonate and recombinant human bone morphogenetic protein 2 on bone healing of rat calvarial defects

Antibody	Time/week	Groups
Antibody	Time/week	Group 1	Group 2	Group 3	Group 4
Collagen type I	2	++	+++	+++	+
	4	++	++	++	++
	8	+++	+++	+++	+
	2	++	++	++	+
OPG	4	+/++	++	+/++	+
	8	++	++	+++	+
	2	++	++	+	++
RANKL	4	++	+++	−/+	++
RANKL	8	+	+	+	++

(−; no immunoreactivity, +; weak immunoactivity, ++; moderate immunoactivity, +++; strong immunoactivity, Abbreviations: OPG osteoprotegerin, RANKL receptor activator nuclear factor κB ligand)

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