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Table 3 Clinical features and bisphosphonate history of patients

From: Bisphosphonate-related osteonecrosis of the jaw in metastatic breast cancer patients: a review of 25 cases

Case number Age Sex Chief complaint Location Trigger event Stage BP therapy Dose Injection times Comorbid disease
1 45 F Itching sensation Maxilla Extraction 1 Zolendronate 4 mg/monthly 44 -
2 53 F Pain, swelling Maxilla Extraction 2 Zolendronate 4 mg/monthly 41 Hypertension
3 58 F Pain, Swelling Mandible Endo 2 Zolendronate 4 mg/monthly 3 -
4 55 F Swelling, unhealing extraction socket Mandible Extraction 0 Zolendronate 4 mg/monthly 7 -
5 70 F Pain, swelling, pus discharge Mandible Implant 2 Zolendronate 4 mg/monthly 18 Diabetes mellitus, hypertension
6 59 F Pain, pus discharge Maxilla Extraction 2 Zolendronate 4 mg/monthly 20 Hypertension
7 67 F Pain, pus discharge Maxilla Extraction 0 Zolendronate 4 mg/monthly 24 Hypertension
8 50 F Pus discharge, unhealing implantation site Mandible Implant 0 Zolendronate 4 mg/monthly 114 -
9 61 F Pain, swelling, pathologic fracture Mandible Extraction 3 Zolendronate 4 mg/monthly 7 Diabetes mellitus
10 51 F Pain Maxilla Extraction 2 Zolendronate 4 mg/monthly 49 Diabetes mellitus
11 55 F Pain Mandible Extraction 2 Zolendronate 4 mg/monthly 14 -
12 52 F Tooth mobility Mandible Extraction 0 Zolendronate 4 mg/monthly 67 -
13 67 F Pain, tooth mobility Bilateral mandible Extraction 2 Zolendronate 4 mg/monthly 20 -
14 38 F Pus discharge Maxilla Extraction 2 Zolendronate 4 mg/monthly 21 -
15 65 F Pus discharge Maxilla Extraction 2 Zolendronate 4 mg/monthly 23 -
16 49 F Pus discharge Mandible Extraction 0 Zolendronate 4 mg/monthly 13 Hypothyroidism
17 49 F Pain Mandible Extraction 2 Zolendronate 4 mg/monthly 58 -
18 48 F Pain, swelling Maxilla and mandible Extraction 2 Zolendronate 4 mg/monthly 47 -
19 70 F Pain, unhealing
extraction socket
Bilateral maxilla and mandible Extraction 2 Zolendronate 4 mg/monthly 52 -
20 42 F Pus discharge Maxilla and mandible Extraction 2 Zolendronate 4 mg/monthly 40 -
21 49 F Pain Maxilla Spontaneous 0 Zolendronate 4 mg/monthly 9 -
22 48 F Pain, pus discharge Mandible Extraction 2 Zolendronate 4 mg/monthly 43 -
23 55 F Pain Mandible Spontaneous 2 Zolendronate 4 mg/monthly 10 -
24 54 F Pain Maxilla Extraction 2 Zolendronate 4 mg/monthly 48 -
25 74 F Swelling, intraoral fistula Mandible Spontaneous 2 Zolendronate 4 mg/monthly 25 -
  1. F female