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Table 1 Measurements of the rat calvarial defect

From: Chitin-fibroin-hydroxyapatite membrane for guided bone regeneration: micro-computed tomography evaluation in a rat model

Measurement

Time

Membrane

P value

Void

Bio-gide®

CNF/HAP

BV

2 weeks

1.79 ± 0.52A

5.73 ± 1.74B

5.08 ± 1.10B

0.001*

4 weeks

3.16 ± 0.68A

6.49 ± 2.65B

5.63 ± 2.22AB

0.027*

8 weeks

4.78 ± 2.03A

8.59 ± 1.66B

7.43 ± 1.28B

0.007*

BMD

2 weeks

0.45 ± 0.04A

0.62 ± 0.04B

0.59 ± 0.10B

0.029*

4 weeks

0.58 ± 0.06A

0.79 ± 0.05B

0.67 ± 0.01C

0.019*

8 weeks

0.67 ± 0.08

0.79 ± 0.04

0.76 ± 0.19

0.213

  1. Different uppercase letters indicate statistical difference within the same line; *P < 0.05
  2. BV= bone volume (mm3), BMD= bone mineral density (mg/ml), CNF/HAP= chitin-hydroxyapatite-fibroin membrane