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Table 2 Clinical characteristics of MM patients with MRONJ

From: Medication-related osteonecrosis of the jaw: a preliminary retrospective study of 130 patients with multiple myeloma

No. Stage (sign) locLocation Etiologic factor BP types (duration in months) Treatment Outcomes (stage)
1 II (Bone exposure, pus discharge, pain) Mandible molar Denture irritation Zoledronate, pamidronate (19) I&D, antibiotics, dressing, biopsy Bone exposure (stage I)
2 II (Bone exposure, pus discharge, pain) Mandible molar Pontic irritation Zoledronate, pamidronate (19) Antibiotics, dressing, biopsy Bone exposure (stage I)
3 II (Bone exposure, pus discharge, pain) Mandible molar Tooth extraction Zoledronate (15) I&D, antibiotics, dressing Bone exposure (stage I)
4 II (Bone exposure, pain) Mandible molar Tooth extraction Zoledronate, Pamidronate (69) Antibiotics, Dressing Bone exposure (stage I)
5 II (Bone exposure, pus discharge, pain) Mandible molar Tooth extraction Zoledronate, pamidronate (11) Saucerization I&D, antibiotics, dressing No follow-up
6 I (Bone exposure) Mandible molar Spontaneous Zoledronate, pamidronate (25) Antibiotics, dressing Bone exposure (stage I)
7 II (Bone exposure, pus discharge, pain) Maxilla molar Gingival curettage Zoledronate, pamidronate (40) Antibiotics, dressing Bone exposure with pain (stage II)
8 III (Pain, Osteolytic lesion on Mn. Basal bone) Mandible molar Tooth extraction Pamidronate (8) Antibiotics, dressing No f/u
9 I (Bone exposure) Mandible molar Tooth extraction Zoledronate, pamidronate (17) Antibiotics, dressing, biopsy Bone exposure state (died due to systemic disease)