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Table 2 Clinical characteristics of MM patients with MRONJ

From: Medication-related osteonecrosis of the jaw: a preliminary retrospective study of 130 patients with multiple myeloma

No.

Stage (sign)

locLocation

Etiologic factor

BP types (duration in months)

Treatment

Outcomes (stage)

1

II (Bone exposure, pus discharge, pain)

Mandible molar

Denture irritation

Zoledronate, pamidronate (19)

I&D, antibiotics, dressing, biopsy

Bone exposure (stage I)

2

II (Bone exposure, pus discharge, pain)

Mandible molar

Pontic irritation

Zoledronate, pamidronate (19)

Antibiotics, dressing, biopsy

Bone exposure (stage I)

3

II (Bone exposure, pus discharge, pain)

Mandible molar

Tooth extraction

Zoledronate (15)

I&D, antibiotics, dressing

Bone exposure (stage I)

4

II (Bone exposure, pain)

Mandible molar

Tooth extraction

Zoledronate, Pamidronate (69)

Antibiotics, Dressing

Bone exposure (stage I)

5

II (Bone exposure, pus discharge, pain)

Mandible molar

Tooth extraction

Zoledronate, pamidronate (11)

Saucerization I&D, antibiotics, dressing

No follow-up

6

I (Bone exposure)

Mandible molar

Spontaneous

Zoledronate, pamidronate (25)

Antibiotics, dressing

Bone exposure (stage I)

7

II (Bone exposure, pus discharge, pain)

Maxilla molar

Gingival curettage

Zoledronate, pamidronate (40)

Antibiotics, dressing

Bone exposure with pain (stage II)

8

III (Pain, Osteolytic lesion on Mn. Basal bone)

Mandible molar

Tooth extraction

Pamidronate (8)

Antibiotics, dressing

No f/u

9

I (Bone exposure)

Mandible molar

Tooth extraction

Zoledronate, pamidronate (17)

Antibiotics, dressing, biopsy

Bone exposure state (died due to systemic disease)