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Fig. 4 | Maxillofacial Plastic and Reconstructive Surgery

Fig. 4

From: Angiogenesis in newly regenerated bone by secretomes of human mesenchymal stem cells

Fig. 4

Immunohistochemical staining of the defects in 5-mm defect samples. In the MSC-CM group, many CD31-positive cells (red) are seen in the defect. FLK-1-positive cells are arranged in a circular shape and CD105-positive cells (green) are observed near the CD105-positive cells. From the hematoxylin and eosin (H-E) images of the MSC-CM group, these CD31 and FLK-1-positive cells were considered to form the blood vessels. In the MSC-CM and MSC-CM + anti-VEGF groups, few CD31-, FLK-1-, and CD105-positive cells were seen in the specimens

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