Maxillofacial Plastic and Reconstructive Surgery

Table 1 Calculation of DCE doses for a mouse to achieve equivalence with human adults

From: In vivo protein expression changes in mouse livers treated with dialyzed coffee extract as determined by IP-HPLC

Coffee	Ordinary coffee extract	Dialyzed coffee extract (DCE)
Caffeine concentration	120 mg/150 mL	60 mg/150 mL
Dialysis coefficient		50%
One cup for a human adult (60 kg, 59.4 L)	150 mL	300 mL (DCE-1)
DCE-1 to 30 g mouse		0.15 mL
DCE-2.5 to 30 g mouse		0.375 mL
DCE-5 to 30 g mouse		0.75 mL
DCE-10 to 30 g mouse		1.5 mL

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