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Table 2 Main characteristics of bisphosphonates (BPs)

From: Pharmacoepidemiology and clinical characteristics of medication-related osteonecrosis of the jaw

Type of BPs Relative potency Average dose administered (mg) Bone absorption rate Average dose deposited in bone (mg) Weight dose deposited/1000
Pamidronate 100 142,750 1% (PO) 1427.5 142.75
300 70% (IV) 210 21
Alendronate 1000 17,633 1% (PO) 176 176
Ibandronate 10,000 6900 1% (PO) 69 690
51.43 70% (IV) 36 360.01
Risendronate 20,000 9861.25 1% (PO) 98.61 1972.25
Zoledronate 100,000 62.67 70% (IV) 43.87 4386.90
  1. Relative potency, average dose administered, bone absorption rate, average dose deposited in Bone, weight dose deposited/1000 in this study