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Maxillofacial Plastic and Reconstructive Surgery

Table 3 Weight dose deposited according to MRONJ Clinical Stage and Treatment Response

From: Pharmacoepidemiology and clinical characteristics of medication-related osteonecrosis of the jaw

 

Weight dose deposited (SD)

Ln [weight dose deposited] (SD)

P

MRONJ stage

 I

195.15 (260.97)

4.63 (1.18)

< 0.001

 II

589.82 (746.43)

5.77 (1.11)

 III

4379.89 (7317.72)

7.28 (1.54)

Treatment response

 Complete

351.18 (385.32)

 

< 0.05

 Delayed

1328.92 (2607.23)

 

 None

2532.48 (6604.07)

 
  1. ANCOVA adjusted age, sex MRONJ site, medical comorbidities
  2. Results are shown as mean (SD)
  3. Values of the weight dose deposited was applied logarithm for normal distribution
  4. The higher the stage, the higher the weighted total accumulation was found (P <  0.001)
  5. Higher weighted total accumulation was found as the response to therapy was delayed or none (P <  0.05)
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