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Table 3 Weight dose deposited according to MRONJ Clinical Stage and Treatment Response

From: Pharmacoepidemiology and clinical characteristics of medication-related osteonecrosis of the jaw

  Weight dose deposited (SD) Ln [weight dose deposited] (SD) P
MRONJ stage
 I 195.15 (260.97) 4.63 (1.18) < 0.001
 II 589.82 (746.43) 5.77 (1.11)
 III 4379.89 (7317.72) 7.28 (1.54)
Treatment response
 Complete 351.18 (385.32)   < 0.05
 Delayed 1328.92 (2607.23)  
 None 2532.48 (6604.07)  
  1. ANCOVA adjusted age, sex MRONJ site, medical comorbidities
  2. Results are shown as mean (SD)
  3. Values of the weight dose deposited was applied logarithm for normal distribution
  4. The higher the stage, the higher the weighted total accumulation was found (P <  0.001)
  5. Higher weighted total accumulation was found as the response to therapy was delayed or none (P <  0.05)