Skip to main content

Table 4 Weight dose deposited according to MRONJ Clinical Stage and Treatment Response

From: Pharmacoepidemiology and clinical characteristics of medication-related osteonecrosis of the jaw

  Estimates (SE) 95% CI Significance
Weight dose deposited according to MRONJ Clinical Stage
 Ln [weighted dose] 1.113 (0.247) 0.63 1.60 < 0.001
 Age − 0.043 (0.030) − 0.10 0.02 > 0.05
 Sex − 1.033 (1.168) − 3.32 1.23 > 0.05
 MRONJ site 1.635 (1.344) − 1.00 4.27 > 0.05
 Medical comorbidity 0.089 (0.539) − 0.97 1.15 > 0.05
 ONJ stage 5.921 (2.898) 0.24 11.60 < 0.05
Weight dose deposited according to treatment response
 Ln [weighted dose] 0.443 (0.160) 0.13 0.76 < 0.05
 Age 0.012 (0.023) − 0.03 0.06 > 0.05
 Sex 0.237 (0.918) − 1.56 2.04 > 0.05
 MRONJ site − 0.917 (1.135) − 3.14 1.31 > 0.05
 Medical comorbidity 0.476 (0.440) − 0.39 1.34 > 0.05
 Tx. response 4.757 (2.354) 0.14 9.37 < 0.05
  1. Ordinal logistic regression adjusted age, sex MRONJ site, medical comorbidities
  2. Weighted dose depositions were found to have a significant effect on ONJ staging and treatment response, measured by ordinal logistic regression, with 95% of confidence level (P < 0.05)