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Table 4 Weight dose deposited according to MRONJ Clinical Stage and Treatment Response

From: Pharmacoepidemiology and clinical characteristics of medication-related osteonecrosis of the jaw

 

Estimates (SE)

95%

CI

Significance

Weight dose deposited according to MRONJ Clinical Stage

 Ln [weighted dose]

1.113 (0.247)

0.63

1.60

< 0.001

 Age

− 0.043 (0.030)

− 0.10

0.02

> 0.05

 Sex

− 1.033 (1.168)

− 3.32

1.23

> 0.05

 MRONJ site

1.635 (1.344)

− 1.00

4.27

> 0.05

 Medical comorbidity

0.089 (0.539)

− 0.97

1.15

> 0.05

 ONJ stage

5.921 (2.898)

0.24

11.60

< 0.05

Weight dose deposited according to treatment response

 Ln [weighted dose]

0.443 (0.160)

0.13

0.76

< 0.05

 Age

0.012 (0.023)

− 0.03

0.06

> 0.05

 Sex

0.237 (0.918)

− 1.56

2.04

> 0.05

 MRONJ site

− 0.917 (1.135)

− 3.14

1.31

> 0.05

 Medical comorbidity

0.476 (0.440)

− 0.39

1.34

> 0.05

 Tx. response

4.757 (2.354)

0.14

9.37

< 0.05

  1. Ordinal logistic regression adjusted age, sex MRONJ site, medical comorbidities
  2. Weighted dose depositions were found to have a significant effect on ONJ staging and treatment response, measured by ordinal logistic regression, with 95% of confidence level (P < 0.05)