Variables | Case (%) | Control (%) | Odds ratio (CI = 95%) | P value | Adjusted ORa (95% CI) | P value | |
---|---|---|---|---|---|---|---|
Sex female (male, reference category) | 171 (53) | 204 (51) | 1.081 (0.806–1.450) | 0.60354 | 1.007 (0.742–1.367) | 0.964131 | |
History of abortion/miscarriage | 42 (13) | 28 (7) | 1.986 (1.201–3.283) | 0.007475 | 1.339 (0.761–2.355) | 0.311026 | |
Consanguineous marriage | 119 (36) | 93 (23) | 1.926 (1.393–2.662) | 0.00735 | 1.854 (1.329–2.586) | 0.0275 | |
Systemic diseases | 36 (11) | 32 (8) | 1.443 (0.874–2.380) | 0.151417 | 1.307 (0.773–2.211) | 0.318197 | |
Medication during pregnancy | 122 (38) | 124 (31) | 1.358 (0.997–1.850) | 0.05254 | 1.339 (0.971–1.847) | 0.074891 | |
Complications during pregnancy | 92 (29) | 88 (22) | 1.412 (1.007–1.980) | 0.045517 | 1.293 (0.901–1.856) | 0.162789 | |
Maternal age (years) | < 25 | 43 (14) | 48 (12) | 1.483 (0.904–2.432) | 0.118696 | 1.608 (0.952–2.717) | 0.075617 |
26–30 (reference) | 87 (27) | 136 (34) | 1 | – | 1 | - | |
30–35 | 102 (31) | 132 (33) | 1.063 (0.939–1.204) | 0.335031 | 1.062 (0.931–1.213) | 0.369834 | |
> 35 | 91 (28) | 84 (21) | 1.151 (1.042–1.272) | 0.005646 | 1.139 (1.027–1.264) | 0.01355 | |
Paternal age (years) | < 25 | 29 (9) | 44 (11) | 1.023 (0.584–1.792) | 0.93643 | 1.092 (0.602–1.982) | 0.771544 |
26–30 (reference) | 67 (21) | 104 (26) | 1 | – | 1 | – | |
30–35 | 122 (38) | 144 (36) | 1.098 (0.964–1.251) | 0.158797 | 1.098 (0.958–1.260) | 0.179591 | |
> 35 | 105 (32) | 108 (27) | 1.106 (0.998–1.225) | 0.053716 | 1.105 (0.993–1.230) | 0.067299 | |
Birth order | 1st (reference) | 158 (49) | 156 (39) | 1 | – | 1 | – |
2nd | 83 (26) | 140 (35) | 0.760 (0.638–0.906) | 0.002204 | 0.789 (0.656–0.948) | 0.011335 | |
3rd | 51 (16) | 72 (18) | 0.887 (0.771–1.021) | 0.096105 | 0.914 (0.791–1.057) | 0.225932 | |
4th and higher | 31 (9) | 32 (8) | 0.997 (0.870–1.142) | 0.963656 | 0.988 (0.856–1.142) | 0.872614 | |
Total | 323(100) | 400 (100) | – | –- | – | – |