|
Variables
|
Case (%)
|
Control (%)
|
Odds ratio (CI = 95%)
|
P value
|
Adjusted ORa (95% CI)
|
P value
|
|---|
|
Sex female (male, reference category)
|
171 (53)
|
204 (51)
|
1.081 (0.806–1.450)
|
0.60354
|
1.007 (0.742–1.367)
|
0.964131
|
|
History of abortion/miscarriage
|
42 (13)
|
28 (7)
|
1.986 (1.201–3.283)
|
0.007475
|
1.339 (0.761–2.355)
|
0.311026
|
|
Consanguineous marriage
|
119 (36)
|
93 (23)
|
1.926 (1.393–2.662)
|
0.00735
|
1.854 (1.329–2.586)
|
0.0275
|
|
Systemic diseases
|
36 (11)
|
32 (8)
|
1.443 (0.874–2.380)
|
0.151417
|
1.307 (0.773–2.211)
|
0.318197
|
|
Medication during pregnancy
|
122 (38)
|
124 (31)
|
1.358 (0.997–1.850)
|
0.05254
|
1.339 (0.971–1.847)
|
0.074891
|
|
Complications during pregnancy
|
92 (29)
|
88 (22)
|
1.412 (1.007–1.980)
|
0.045517
|
1.293 (0.901–1.856)
|
0.162789
|
|
Maternal age (years)
|
< 25
|
43 (14)
|
48 (12)
|
1.483 (0.904–2.432)
|
0.118696
|
1.608 (0.952–2.717)
|
0.075617
|
|
26–30 (reference)
|
87 (27)
|
136 (34)
|
1
|
–
|
1
|
-
|
|
30–35
|
102 (31)
|
132 (33)
|
1.063 (0.939–1.204)
|
0.335031
|
1.062 (0.931–1.213)
|
0.369834
|
|
> 35
|
91 (28)
|
84 (21)
|
1.151 (1.042–1.272)
|
0.005646
|
1.139 (1.027–1.264)
|
0.01355
|
|
Paternal age (years)
|
< 25
|
29 (9)
|
44 (11)
|
1.023 (0.584–1.792)
|
0.93643
|
1.092 (0.602–1.982)
|
0.771544
|
|
26–30 (reference)
|
67 (21)
|
104 (26)
|
1
|
–
|
1
|
–
|
|
30–35
|
122 (38)
|
144 (36)
|
1.098 (0.964–1.251)
|
0.158797
|
1.098 (0.958–1.260)
|
0.179591
|
|
> 35
|
105 (32)
|
108 (27)
|
1.106 (0.998–1.225)
|
0.053716
|
1.105 (0.993–1.230)
|
0.067299
|
|
Birth order
|
1st (reference)
|
158 (49)
|
156 (39)
|
1
|
–
|
1
|
–
|
|
2nd
|
83 (26)
|
140 (35)
|
0.760 (0.638–0.906)
|
0.002204
|
0.789 (0.656–0.948)
|
0.011335
|
|
3rd
|
51 (16)
|
72 (18)
|
0.887 (0.771–1.021)
|
0.096105
|
0.914 (0.791–1.057)
|
0.225932
|
|
4th and higher
|
31 (9)
|
32 (8)
|
0.997 (0.870–1.142)
|
0.963656
|
0.988 (0.856–1.142)
|
0.872614
|
|
Total
|
323(100)
|
400 (100)
|
–
|
–-
|
–
|
–
|
- C
- aOR is adjusted for all other factors in the table
