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Table 1 Articles included for this systematic review and quantity of saliva required for exosomal miR detection

From: Salivary exosomal microRNAs as biomarkers for head and neck cancer detection—a literature review

Author and publication year

Title

Study type

Saliva sample (ml)

Byun et al. 2015 [15]

Diagnostic profiling of salivary exosomal microRNAs in oral lichen planus patients

Saliva

5

Langevin et al. 2017 [16]

Comprehensive microRNA-sequencing of exosomes derived from head and neck carcinoma cells in vitro reveals common secretion profiles and potential utility as salivary biomarkers

Saliva and in vitro

2

Gai et al. 2018 [17]

Salivary extracellular vesicle-associated miRNAs as potential biomarkers in oral squamous cell carcinoma

Saliva

-

He et al. 2020 [18]

Salivary exosomal miR-24-3p serves as a potential detective biomarker for oral squamous cell carcinoma screening

Saliva, in vitro and tumor tissue

5

Farag et al. 2021 [19]

MiR-134/miR-200a-derived salivary exosomes are novel diagnostic biomarkers of oral squamous cell carcinoma

Saliva

3

  1. “-” = unspecified