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Table 2 QUADAS-2 assessment of the risk bias and applicability for the included articles in this review

From: Salivary exosomal microRNAs as biomarkers for head and neck cancer detection—a literature review

Study Risk of bias Applicability concerns
Patient selection Index test Reference standard Flow and timing Patient selection Index test Reference standard
Byun et al. [15] ? + + + + + +
Langevin et al. [16] + + + + + + +
Gai et al. [17] + ? + + + + +
He et al. [18] + + + + + + +
Farag et al. [19] + + + + + + +
  1. + Low risk; - High Risk; ? Unclear