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Fig. 4 | Maxillofacial Plastic and Reconstructive Surgery

Fig. 4

From: 4-Hexylresorcinol: pharmacologic chaperone and its application for wound healing

Fig. 4

Comparison between systemic administration and topical application. Systemic administration of 4HR can be done via per os, subcutaneous, or intravenous route. In any case, administered 4HR will introduce into vessel. The decoy protein for 4HR can be found in anywhere. When 4HR is bound to decoy protein, the amount of delivery to the target organ will be decreased. If wound healing is aimed, topical delivery of 4HR will be much better. If target disease is osteoporosis, 4HR should be administered systemically. In this case, smart tool for drug delivery may be required to avoid unnecessary off-target effect

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