From: Manifestation and treatment in a cleidocranial dysplasia patient with a RUNX2 (T420I) mutation
1. Multiple unerupted, abnormal teeth. |
2. Narrow ascending ramus, with near parallel-sided anterior and posterior borders, sometimes narrowing towards the coronoid process and condyle. |
3. Slender, pointed coronoid process often facing upwards and posteriorly. |
4. Thin zygomatic arch with a severe downward tilt, sometimes discontinuous at the site of the zygomatico-temporal suture. |
5. Maxillary sinuses very small or absent. The infra-orbital rim appears lower than normal in relation to the teeth. |
6. Downward tilting floor of nose at the site of the anterior nasal spine to a marked V-shape. |
7. Coarse trabeculation of mandible. |
8. Increased density of alveolar crestal bone overlying unerupted teeth. |
9. Increased density of the ascending ramus between the anterior border of the mandible and the inferior dental canal. |