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Table 1 Characteristics of PD-L1/p53/CK17 expression in patients with oral squamous cell carcinoma

From: PD-L1 expression correlated with p53 expression in oral squamous cell carcinoma

Characteristics PD-L1 expression in TCsp53 expressionCK17 expression
CasesPositive ( ≥5%)Negative (<5%)P valuePositive ( ≥10%)Negative (<10%)P valueStrong ( ≥60%)Weak (<60%)P value
GenderMale2914151.002090.374250.27
Female201010 119 614 
Age<65 years2212131.0015100.765201.00
>65 years271212 168 519 
T stageT1–T3341519 1816 5290.12
T414860.521220.049*59 
Unknown110 10 01 
N stageN (+)201010 137 416 
N (-)2813151.0017111.006221.00
Unknown11  1   1 
M stageM0482225 2918 01 
M10100.47101.0010371.00
Unknown110 10 01 
TNM stageI–III301317 1515 426 
IV181080.551530.03*6120.14
Unknown110 10 01 
DifferentiationWell351916 2015 827 
Moderate11470.54830.311100.47
Poor312 30 12 
Mode of invasionGrade 1321 21 21 
Grade 2945 36 18 
Grade 317980.961160.213140.37
Grade 4C1679 115 313 
Grade 4D422 40 13 
PD-L1 expression in TCsPositive24 21100.0009*17220.17
Negative25315 73 
PD-L1 expression in TILsPositive28217< .0001*2170.0720190.15
Negative21318 1110 82 
p53 expressionPositive3121100.0009* 22170.06
Negative18315 91 
CK17 expressionWeak3917220.1722170.06 
Strong1073 91 
  1. P value : χ2 test and Fisher's exact test were used. *P<0.05 was defined as significantly different in statistical analysis
  2. Unknown includes those cases with Tx, Nx, Mx and TNM status and they were excluded from statistical analysis