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Maxillofacial Plastic and Reconstructive Surgery
Fig. 2 | Maxillofacial Plastic and Reconstructive Surgery

Fig. 2

From: Influence of biodegradable polymer membrane on new bone formation and biodegradation of biphasic bone substitutes: an animal mandibular defect model study

Fig. 2

Histologic findings on the experimental and control groups at 4 and 8 weeks postoperatively. Newly formed bone (green) and remaining graft (black) volumes were calculated based on the total area (12 mm2 area, red square), respectively. The biodegradation in osteon was pointed as arrow. At 4 weeks, immature new bone was formed around graft material, large amount of woven bone with small portion of mature bone was formed around graft material. At 8 weeks, large amount of new bone was formed around graft material, and trabecular containing many osteoblasts were detected around graft material. The Osteoguide showed resorption progression and calcium particles are observed on the Osteoguide area without inflammation tissue. The covered shape of osteoguide was irregular pattern. There was shown to delayed new bone formation as fibrous tissue formed earlier than osteogenesis

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