Efficacy and safety of rhBMP/β-TCP in alveolar ridge preservation: a multicenter, randomized, open-label, comparative, investigator-blinded clinical trial

Maxillofacial Plastic and Reconstructive Surgery

Table 6 Summary of adverse events in this clinical trial

	Test group (N = 43)	Control group (N = 45)	Total (N = 48)
Patients with adverse events	2 (4.65)	7 (15.56)	9 (10.23)
95% CI	0.57, 15.81	6.49, 29.46	4.78, 18.53
p value*			0.1577
Severity of cases with adverse events
Mild	2	9	11
Moderate	0	2	2
Severe	0	0	0
Relationship to the grafted material
Definitely related	0	0	0
Probably related	0	1	1
Possibly related	0	0	0
Possibly not related	0	0	0
Definitely not related	2	10	12
Unknown	0	0	0

^*Fisher’s exact test
Patients with adverse events are presented as “number of patients (percentage of patients) [number of events]” and others are presented as “number of events”